RNA-Seq: DESeq2 library("DESeq2") library(ggplot2) dds

Converting Human to mouse genes names with BiomaRt human -> mouse #install if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("biomaRt") #human -> mouse require("biomaRt") human = useMart("ensembl", dataset = "hsapiens_gene_ensembl") mouse = useMart("ensembl", dataset = "mmusculus_gene_ensembl") x Human 으로 하고싶다면 반대로 하면 된다. #getLDS :Retrieves informa..

DAVID Functional Annotation Tool Reference:DAVID: Functional Annotation Result Summary (ncifcrf.gov) DAVID: Functional Annotation Result Summary Key Concepts: Term/Gene Co-Occurrence Probability Ranking functional categories based on co-occurrence with sets of genes in a gene list can rapidly aid in unraveling new biological processes associated with cellular functions and pathways. DAVID 6.8 al..

Genotype The genetic makeup of an individual. Refers to the information contained on two alleles in the cell. (Examples DNA, susceptibility to diseases) Phenotype Detectable expression of the genotype. An expressed and observable trait. (Examples Hair color, eye color, weight, the ability to roll one's tongue) Reference:Genotype vs Phenotype - Difference and Comparison | Diffen Genotype vs Pheno..

Gene mapping Gene mapping describes the methods used to identify the locus of a gene and the distances between genes. Gene mapping can also describe the distances between different sites within a gene. The essence of all genome mapping is to place a collection of molecular markers onto their respective positions on the genome. Molecular markers come in all forms. Genes can be viewed as one speci..

Alignment (bioinformatics) A way of arranging DNA, RNA or protein sequences in order to identify regions of similarity. Reference:https://en.wiktionary.org/wiki/alignment alignment - Wiktionary English[edit] In alignment and out of alignment Etymology[edit] French alignement Morphologically align +‎ -ment Pronunciation[edit] alignment (countable and uncountable, plural alignments) An arrangement..

DNA sequencing DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has..

Morphology (biology) Morphology is a branch of biology dealing with the study of the form and structure of organisms and their specific structural features. This includes aspects of the outward appearance (shape, structure, colour, pattern, size), i.e. external morphology (or eidonomy), as well as the form and structure of the internal parts like bones and organs, i.e. internal morphology (or an..

Phenotype In genetics, the phenotype is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code,..

Gene ontology The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for eas..